Cymbalta Withdrawal Support and Cymbalta Side Effects Help: Help Me - Cymbalta Withdrawal Support and Cymbalta Side Effects Help

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Help Me Cymbalta could be hurting me?

#1 User is offline   MaureenV 

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    Am trying to get off Cymbalta 30mg and wondering about brain zaps.

Posted 22 April 2010 - 04:52 AM

View PostCarrie, on 21 April 2010 - 11:50 PM, said:

I am afraid. I already have these symptoms you all describe but I knew nothing about this. Worse yet, I'm heavily medicated on the drug for very serious medical problems (not so much mental but have extreme anxiety now). I had no idea. My doctor has never tested my liver but I am yellow and can't stop getting so sick. I'm 5'7" and just went from 135 pounds to 110 overnight. I can't continue to take this "worst EVER never-ending flu" feeling that is depressing the heck our of me. I'm on 120 mg a day and I've read and read and have seen no other patient on that high of a dosage. I've retired at 50 because I am so sick. Could this be hurting me -- Cymbalta itself? Please advise me as I'm very ill and no one is treating the problem, just the symptoms. I am on my own right now and I don't know how to deal with this. I've lost my career after being at the top of my field and walked out on my 22-year marriage (Being sick was only partially to blame for either one: I am married to an extemely anxiety inducing husband0. Can someone who knows something email me directly? Carrie -- ctuft2005@yahoo.com I THOUGHT CYMBALTA was supposed to help. All 10 of my doctors know I'm on it and not one said anything about this to me. PLEASE HELP ME!


Cymbalta dose goes up to 150mg a day. The doses I've seen people on (through this board) are 20mg (rare) to 150mg (also rare). Most drugs are processed by the liver, and liver disease is of concern for almost any drug, so if you have any concerns in that area, insist on tests.


I believe even the drug company themselves say that there's often not much benefit in going from 60mg to 120mg. Were you put on to 120mg fairly quickly? Or were you on a lower dose which got increased at some stage? In which case, did the higher dose make much difference.


The reason I ask is because people often find they don't have too much problem getting down to 60mg or 30mg from higher doses. HOWEVER, perhaps they're just the ones for whom the higher dose didn't help much anyway. Who knows? All we've got on this board are anecdotal examples of the problems with Cymbalta.

If you do decide you want off, keep in mind that many doctors are not as familiar with the problems that can occur for some people. They suggest things like taking it alternate days, which doesn't work for those with serious withdrawal problems, because it's only got a short half life.

I'm not saying this is going to work for you, because I'm only going on what I've read of the experiences of others who've posted here, but you could try dropping to 90mg per day and see what happens.

Many find that the withdrawal effects don't really kick in for up to a week, so don't even think about further drops until you know how you're feeling after a few weeks of the reduction (if that's what you do).

If at any point you feel bad, you can add back some of the dose, without going right back up to 120mg.

Firstly, though, you need to get that liver stuff sorted. I haven't the faintest idea how that would affect any withdrawal symptoms.

KEEP IN TOUCH>

regards, Maureen.
You can't stop the waves, but you can learn to surf.
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#2 User is offline   tina 

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    cymbalta withdrawal

Posted 09 June 2010 - 02:48 PM

If you are yellow (jaundice)then your liver has sustained injury. I hope that you insisted on liver tests. One of the contraindications for cymbalta if that if you have a compromised liver you should not use it. And yes, in some people it can seriously harm a healthy liver. If the yellow has gone away, that does not necessarily mean that the liver is OK. You still need tests.

Good luck.

tina
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#3 User is offline   Junior 

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    I am a sufferer of depression and GAD. After 20 years of suffering with undiagnosed GAD (to be fair to the medical profession, it wasn't in the DSM back then) I stumbled upon Aropax following a bout of depression. Having had the therapy I badly needed at the time, I came good and did well on Aropax for 11 years. Last year I started having difficulty with sleeping and thought I was suffering the poop out effect, so I switched to Lexapro. A few months later I realised it was causing me more problems than it was solving so my GP agreed to give me a referral to a psychiatrist - so we could work out the best medicine for me. Nearly 3 weeks on Cymbalta and I've stopped already. I've had restlessness, increased insomnia (I now recognise that there is more to that), an inability to concentrate (the opposite of the real me) and nausea. I want to converse with others who are going through the same issues with medication.

Posted 09 June 2010 - 04:52 PM

Hi Carrie

These drugs are metabolised by the liver - there is a particular enzyme. Some have low levels of the enzyme and suffer greater withdrawal probs as a result. In your case it sounds like the level of the drug was just way too high for your liver to be able to metabolise.

You need to reduce the dose of Cymbalta - but slowly. You could try dropping from 150 to 120 and waiting a couple of weeks. Please don't come off cold turkey though as you could do more harm to yourself than good.

And get those liver function tests done.

I went to a naturopath and she has me on a liver tonic, among other things. Food for thought.

Good luck
Junior
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