cookie, on 29 April 2010 - 06:02 AM, said:
Hi Junior:
Thank you so much for your answer! it really helps.
Imagine I´ve been on cymbalta for 5 years and as -you describe- I´ve develop certain tolerance to it. It is not as effective as at the beginning (thing that I told my psychiatrist, he says that it is not possible, that antidepressants do not just stop working).
In my case this is my second episode of Depression. I had one mild one 8 years ago, and then a strong episode struck 5 years ago.
The reason I started to think about dosage decrease (& weaning) was all the horrible withdrawal symptoms I read on this site. Exactly like you say I thought that cymbalta "brings more problems that being on it solves". I am evaluating what is worse: the Depression symptoms (that i had at the beginning) or the withdrawal symptoms people describe.
I do appreciate your opinion, because you yourself have suffered for many years episodes of Depression & have tried different medications. If you can keep me updated on your progress it will be interesting.
Thank you for the site I´ll check it out
C.
Hi Cookie
Glad I can help.
Yeah, depression is the absolute pits. Give me physical pain any time. It makes sense. The anguish of depression doesn't. And when you are in that state you can't even begin to imagine feeling happy and enjoying life again. Just having a simple conversation can seem impossible because words just don't come. And cognitive tasks? Bah..too hard!
Your Dr is actually right. A/ds don't stop working. The problem is, we become addicted to them and our bodies ask for higher doses. When we don't give in to that, we effectively go into withdrawal. My own experience was that Aropax / Paxil wasn't working as effectively as previous and my mood was lower than it should have been. I wasn't depressed but a bit low and sleep was an issue. Took me a while to figure out what was going on and when I did, I spoke to my Dr and we decided I would wean off and switch to another a/d. I ended up going from Paxil to Lexapro to which I had a bad reaction (inner restlessness, impaired concentration, impaired short term memory, feeling of being electrically charged, low mood and eventually the urge to slit my wrists!) then over to Cymbalta. Cymbalta disrupted my sleep pattern and gave me GI distress. I cold turkeyed it after only 19 days on 60mg and suffered horrendous withdrawal. By that time my brain chemistry was so up the pole that no matter what I did, I just could NOT get a decent night's sleep. I was forced to go back on Paxil to stabilise. That and 5 diff tabs that my naturopath prescribed. I've learned a lot in the past 12 months and that is why I hang around here. To help others. I should also mention that I'm not generally sensitive to drugs or allergy prone so I've only suffered a small percentage of what some people go through.
Oh, and because drug companies fund the research into their drugs, there are no studies on either long-term a/d use or long-term withdrawal effects. Therefore, doctors believe that 'discontinuation syndrome' only lasts 2-4 weeks and that any return of symptoms cannot be withdrawal. It must be a return of the original symptoms...... You can see how people end up on a merry go round of different drs, drugs and symptoms. A merry go round that can take years to recover from.
There are some good psychological therapies for treating depression. Not just during the episode but to prevent future ones. If you want to come off Cymbalta, maybe look into one of the more popular ones - cognitive behaviour therapy.
Talk more soon
Junior