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New Study, By Eli Lilly: "antidepressant Drugs Cause Worse Depression"


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#1 FiveNotions

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Posted 22 December 2014 - 09:24 PM

This article is from an Indian publication, and after the discussion of the study, it devolves into a promo piece for SAMe and other "enzymes" and supplements. I'll find the actual study and post it here.
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Antidepressant drugs cause worse depression: Study
The Nation (India), 12/22/2014
http://nation.com.pk...epression-study

From the article:

A recent industry-funded study on antidepressant drugs has revealed that the medications can cause roughly 20 percent of patients to get worse depression symptoms than if they simply took nothing.

The study, which was largely controlled by drug giant Eli Lilly, is an eye-opener for those who still put their faith in antidepressants like Cymbalta (duloxetine), which carry with them life-altering side effects.


Ralitza Gueorguieva, lead author of the study from the Yale University School of Health, and her colleagues conducted trials on 2,500 people, all of whom were given either Cymbalta, various other antidepressant drugs, or a drug-free placebo for two months. At the conclusion of the study, most of those who received the placebo saw a gradual improvement in their depression symptoms, while nearly 20 percent of those taking antidepressants saw a worsening of their symptoms.

Those taking antidepressants rather than a placebo were grouped into one of two groups — “responders” or “non-responders.” Responders allegedly saw some improvement from the drugs, while non-responders saw no improvement at all. Eighty-four percent of all patients in the drug groups reportedly saw some improvement, while 16 percent saw no improvement at all — and this 16 percent actually saw a worsening of symptoms, as well as various other harmful side effects.

According to the study’s three authors [one of whom] is an employee of Eli Lilly, the company that makes Cymbalta, while another is on the company’s scientific advisory board.

What this all means is that patients who choose to use antidepressants, despite the numerous studies showing that they really do not work and can cause tremendous harm (as well as their doctors, need to pay close attention to what effect the drugs are having.


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#2 FiveNotions

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Posted 22 December 2014 - 09:36 PM

I apologize!! I got snookered! Despite the article saying it's a "recent study," it's actually from 2011 ... and is, I think, the basis for one of the other articles I posted in the past day or two.
 
Here's a link to the full study.... again, I apologize for posting that it's "recent" ...

Trajectories of Depression Severity in Clinical Trials of Duloxetine: Insights Into Antidepressant and Placebo Responses
ARCH GEN PSYCHIATRY/VOL 68 (NO. 12), DEC 2011
https://www.statmode... Psychiatry.pdf

#3 lady2882Nancy

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Posted 23 December 2014 - 01:12 AM

I think what is very telling in this is the statement

 

"According to the study's three authors [one of whom] is an employee of Eli Lilly, the company that makes Cymbalta, while another is on the company's scientific advisory board

 

What this all means is that patients who choose to use antidepressants, despite the numerous studies showing that they really do not work and can cause tremendous harm (as well as their doctors, need to pay close attention to what effect the drugs are having."

 

This just falls in to what many of us now know in that therapy is a better option but how many are ever given the option of anything other than the antidepressants. I think many fall into the false belief that the doctor knows best and don't do any research on what a doctor prescribes. Also the stigma of mental illness has patients looking for a quick fix to their depression.

 

In my opinion if those of us who know better spent more of our efforts educating the general public of the dangers of taking antidepressants and the benefits of therapy instead of attacking the big Pharma we could accomplish more and help more people.


#4 lady2882Nancy

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Posted 23 December 2014 - 01:16 AM

Oh and thanks for the link FN as I posted this on my FB page





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