I know what you mean, and for some people, it works. I mean, wouldnt it be easy for me to take a pill that will make me numb, nothing upsets me, nothing bothers me? That would be so simple, so easy....BUT I have been there done that, my grandchildrens silly sayings and laughter did NOT fill my heart with joy, but I did manage a smile because I knew it would have been funny if I felt something. When my grandchildren would run to me with their arms outstretched, I just reacted, no love or joy felt. I would hate being outside, I never heard the birds, or saw the flowers. I wont live my life like that anymore. As I posted earlier, I would rather get into talk therapy, as painful as its going to be, and pray, in order to get past all of this. I WANT TO LIVE!!!!!! And I AM!
Anybody Else Think It's Weird That...
Started by Lori, May 25 2008 09:38 AM
2 replies to this topic
#2
Amanda01
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Newbie
Posted 03 June 2008 - 08:17 AM
Hi,
This is my first post on your forums, but I have been following for a couple of months. I appreciate all the great information and I attribute your dedication and research (Greybeard) to a lot of my success in getting off Cymbalta... My physician did not even have half this information.
I have no answer as to why the drug does not come in less than 20mg, but as part of my (and others, as I have read) weaning process, I visually halved the 20mg daily, taking 10mg a day for a month, then 10mg every-other-day for another two weeks. I am happy to say that I am now 6 days without a single pill of any sort and I feel OK. The last month was hell. I will post in a different thread; maybe someone will gain some relief from my experiences.
That being said, I wanted to share some interesting info that came across my desk yesterday. I work for a medical company, and this was in our bulk distribution yesterday... see below, but it may have already been posted on the site somewhere and I didn't see it.
""Eli Lilly expects FDA action in the middle of 2009 on its sNDA for serotonin and norepinephrine reuptake inhibitor (SNRI) Cymbalta to manage chronic pain, the company said.
Lilly announced its filing, without confirming the date of the submission, and said it will be evaluated under a standard 10-month review period. Cymbalta (duloxetine HCl) is approved for diabetic peripheral neuropathic pain, major depressive disorder and general anxiety disorder.
The company said its one-year estimate for FDA action reflects the current regulatory environment.
The Cymbalta sNDA is based on three double-blind, randomized trials -- one testing the drug in 230 patients with chronic osteoarthritis pain of the knee and two testing the product in a total of 630 patients with chronic lower back pain, the company said.
The application also includes data from previously completed studies in patients with diabetic peripheral neuropathic pain and fibromyalgia. Cymbalta's application for fibromyalgia is pending at the FDA under standard review. The application was submitted last August with an estimated action date in June.
-- Drug Industry Daily""
Interesting information. I can't wait until someone throws the R&D people at Eli Lilly under the bus. Oops, I said that outloud. DARN!
Amanda
This is my first post on your forums, but I have been following for a couple of months. I appreciate all the great information and I attribute your dedication and research (Greybeard) to a lot of my success in getting off Cymbalta... My physician did not even have half this information.
I have no answer as to why the drug does not come in less than 20mg, but as part of my (and others, as I have read) weaning process, I visually halved the 20mg daily, taking 10mg a day for a month, then 10mg every-other-day for another two weeks. I am happy to say that I am now 6 days without a single pill of any sort and I feel OK. The last month was hell. I will post in a different thread; maybe someone will gain some relief from my experiences.
That being said, I wanted to share some interesting info that came across my desk yesterday. I work for a medical company, and this was in our bulk distribution yesterday... see below, but it may have already been posted on the site somewhere and I didn't see it.
""Eli Lilly expects FDA action in the middle of 2009 on its sNDA for serotonin and norepinephrine reuptake inhibitor (SNRI) Cymbalta to manage chronic pain, the company said.
Lilly announced its filing, without confirming the date of the submission, and said it will be evaluated under a standard 10-month review period. Cymbalta (duloxetine HCl) is approved for diabetic peripheral neuropathic pain, major depressive disorder and general anxiety disorder.
The company said its one-year estimate for FDA action reflects the current regulatory environment.
The Cymbalta sNDA is based on three double-blind, randomized trials -- one testing the drug in 230 patients with chronic osteoarthritis pain of the knee and two testing the product in a total of 630 patients with chronic lower back pain, the company said.
The application also includes data from previously completed studies in patients with diabetic peripheral neuropathic pain and fibromyalgia. Cymbalta's application for fibromyalgia is pending at the FDA under standard review. The application was submitted last August with an estimated action date in June.
-- Drug Industry Daily""
Interesting information. I can't wait until someone throws the R&D people at Eli Lilly under the bus. Oops, I said that outloud. DARN!
Amanda
#3
schmb01
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Worker Bee
Posted 03 June 2008 - 11:10 AM
I find it interesting that the studies to which they refer, are 10 month studies. Cymbalta "worked" for me, as in, I didn't realize I had become a zombie, for about 10 months, then the discontinuation syndrome started while I was still ON the drug. The really scary stuff typically happens after 10 months, and for many, it is years later. What they don't study are those effects, nor the effects on people who then choose to, or have to come off of this drug.
That it "numbs" people to pain is a slanted fact at best, and like GB said, it makes you more numb to feeling anything, or to be more easily managed. This is what terrifies me the most about using this for fibromyalgia or arthritis. The elderly population suffers from these conditions, and I spend a good deal of time with my parents at doctors visits, so I see first hand that doctors get frustrated with the elderly. My Mom needs to lose weight. It would help her pain level, no doubt. She is almost 80, is in chronic daily pain, and is an emotional eater, so it isn't likely that she will be losing anytime soon. I see her doctor getting annoyed about it, and what better drug is there to "calm down" elderly people than one such as Cymbalta? I of course watch their meds like a hawk, and would never allow it to be prescribed, but, my point, after this rambling, is that how many doctors that treat the geriatric population will look at Cymbalta as a wonder drug? How many elderly people with begin having psychiatric disturbances? And, when an elderly person has these kinds of issues, they are written off as "they are getting old". How many elderly people have families that are their health care advocates?
I suppose I could work myself into a complete paranoid meltdown here, but knowing just how horrid my experience with this drug was, I shudder to think of a whole new population of drugged individuals all in the name of "pain management", when the cost is quality of life.
That it "numbs" people to pain is a slanted fact at best, and like GB said, it makes you more numb to feeling anything, or to be more easily managed. This is what terrifies me the most about using this for fibromyalgia or arthritis. The elderly population suffers from these conditions, and I spend a good deal of time with my parents at doctors visits, so I see first hand that doctors get frustrated with the elderly. My Mom needs to lose weight. It would help her pain level, no doubt. She is almost 80, is in chronic daily pain, and is an emotional eater, so it isn't likely that she will be losing anytime soon. I see her doctor getting annoyed about it, and what better drug is there to "calm down" elderly people than one such as Cymbalta? I of course watch their meds like a hawk, and would never allow it to be prescribed, but, my point, after this rambling, is that how many doctors that treat the geriatric population will look at Cymbalta as a wonder drug? How many elderly people with begin having psychiatric disturbances? And, when an elderly person has these kinds of issues, they are written off as "they are getting old". How many elderly people have families that are their health care advocates?
I suppose I could work myself into a complete paranoid meltdown here, but knowing just how horrid my experience with this drug was, I shudder to think of a whole new population of drugged individuals all in the name of "pain management", when the cost is quality of life.
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