This may give us a clue as to why the feeling feverish(body temperature regulation) issues with Cymbalta!
http://en.Wikipedia....Norepinephrine( got here looking up Noradrenergic)
Arrived here from:
This article:
Exacerbation of Posttraumatic Stress Disorder Due to Duloxetine which can be found :
http://WWW.primaryps... ... icleid=385
I am posting the article under : Cymbalta's pros and cons:(just cons) which is from information on the web site www.crazymeds.Com
Be Well !
Cymbalta & body temperature research
Started by iliao93, Sep 13 2008 03:06 PM
1 reply to this topic
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iliao93
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Posted 15 September 2008 - 10:20 AM
In case anyone had trouble accessing the Wikipedia page here is the first part, as Norepinephrine has dule roles I imagine that explains some of the seemingly contradictory symptoms we experience including temperature & breathing issues!
Be Well !
Bobbie
"ALL THAT IS REQUIRED FOR EVIL TO PREVAIL IS FOR GOOD MEN TO DO NOTHING."
P.S. the bold in the following article is by me.
Norepinephrine (INN) (abbreviated norepi or NE) or noradrenaline (BAN) is a catecholamine with dual roles as a hormone and a neurotransmitter.
As a stress hormone, norepinephrine affects parts of the brain where attention and responding actions are controlled. Along with epinephrine, norepinephrine also underlies the fight-or-flight response, directly increasing heart rate, triggering the release of glucose from energy stores, and increasing blood flow to skeletal muscle.
However, when norepinephrine acts as a drug it will increase blood pressure by its prominent increasing effects on the vascular tone (due stimulation of alpha-Receptors). This increase in vascular resistance is triggering a compensatory reflex that overcomes its direct stimulatory effects on the heart. The reflex, called the baroreceptor reflex, results in a drop in heart rate called reflex bradycardia.
Be Well !
Bobbie
"ALL THAT IS REQUIRED FOR EVIL TO PREVAIL IS FOR GOOD MEN TO DO NOTHING."
P.S. the bold in the following article is by me.
Norepinephrine (INN) (abbreviated norepi or NE) or noradrenaline (BAN) is a catecholamine with dual roles as a hormone and a neurotransmitter.
As a stress hormone, norepinephrine affects parts of the brain where attention and responding actions are controlled. Along with epinephrine, norepinephrine also underlies the fight-or-flight response, directly increasing heart rate, triggering the release of glucose from energy stores, and increasing blood flow to skeletal muscle.
However, when norepinephrine acts as a drug it will increase blood pressure by its prominent increasing effects on the vascular tone (due stimulation of alpha-Receptors). This increase in vascular resistance is triggering a compensatory reflex that overcomes its direct stimulatory effects on the heart. The reflex, called the baroreceptor reflex, results in a drop in heart rate called reflex bradycardia.
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