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New Cymbalta Research


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#1 fishinghat

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Posted 23 December 2013 - 03:54 PM

There is new research out on how efficient cymbalta is at controlling norepinephrine and seratonin. This is a 11 day study so doesn;t reflect long-term effects.

 

http://www.ncbi.nlm....pubmed/24346757


#2 equuswoman

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    In the future want 2B off Cymbalta! The physicians are no help. Looking for understanding, support & encouragement as I know this is a difficult process. Want 2 be of help 2 others who will find this site looking for same things as I.

Posted 23 December 2013 - 05:46 PM

11 days wow.... :unsure:


#3 Timbo

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    Recently started tapering off of Cymbalta. Having bad effects and wanted to see if there were any ways to do this without having such a negative impact on my functionality.

Posted 23 December 2013 - 09:54 PM

Thanks for sharing the research, fishinghat!  It appears that only saying that Cymbalta had a significant impact on the Serotonin and Norepinephrine levels.   I think there is probably no question that it accomplishes what it is supposed to accomplish (increasing these levels).   I wonder what other variables were taken into consideration (I can only see the Abstract).  Hopefully, there will be further research regarding the OTHER aspects of the drug.  

 

I saw that FDA archive that indicated gave a pretty scathing review of Eli Lilly for not providing an adequate method of taking peple off of Cymbalta.  But I am curious as to why it is now archived and no longer active?  Does anyone know if there was a lawsuit with the Department of Justice that resulted in the statement being taken down?  It is the best summary (in my opinion) of what all of us are experiencing.  


#4 fishinghat

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Posted 24 December 2013 - 08:54 AM

The key thing that caught my attention in that research was it was documenting the effects in the brain not the body. We have long known the effects on those two neuroreceptors in our body (esp stomach, small intestions, etc) but this is the first research I have seen on the brain. This is important because the brain has a totally different transport system, esp for norepinephrine. there is a string in here somewhere where I believe it was thismoment and I discussed if it worked as well in the brain as well as the body. All I could find at that time was a study on rats, nothing on humans. Turn around and out comes this report just a few weeks later. Weird.





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