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Eli Lilly: Cymbalta R&d Process


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#1 FiveNotions

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Posted 27 June 2014 - 10:05 AM

Case Analysis: Eli Lilly-Developing Cymbalta
http://www.studymode...ta-1067797.html
(Full article access requires payment)

Eli Lilly: Developing Cymbalta
http://www.studymode...lta-704063.html
(Full access requires payment)

This may be a version of the above, appears to be freely available: http://www.scribd.co...e/doc/125719937

[PDF]Cymbalta : EPAR - Scientific Discussion
http://www.ema.europ...WC500036776.pdf
www.ema.europa.eu/docs/en_GB/document.../WC500036776.pdf
Eli Lilly Netherlands B.V. has submitted a Marketing Authorisation Application through the. Centralised Procedure, for the medicinal product CYMBALTA, containing .... develop sexual side effects after several weeks or months of SSRI therapy, ...

Quintiles To Assist Lilly in Commercialization Efforts For Cymbalta in ...
http://www.novaquest...lta-in-the-u-s/
www.novaquest.com/quintiles-to-assist-lilly-in-commercialization-efforts-fo...
Jul 18, 2002 - Eli Lilly and Company (NYSE: LLY) and Quintiles Transnational Corp. ... uncertainties in the process of development and regulatory review.

Patent EP1976844A2 - Improved process for pure duloxetine ...
http://www.google.co...1976844A2?cl=en
Oct 8, 2008 - A process for the preparation of pure Duloxetine hydrochloride ... Eli Lilly's Resolution-Racemization-Recycle Synthesis of Duloxetine for Its Robust Processes' ORGANIC PROCESS RESEARCH & DEVELOPMENT vol. 10, no ...

Eli Lilly: Developing Cymbalta - Case - Harvard Business School
http://www.hbs.edu/f....aspx?num=33849
Anticipating the expiration of its Prozac patent, Eli Lilly has to make tough decisions regarding the development of its next-generation antidepressant drug.

[PDF] Eli Lilly: Developing Cymbalta
http://www.homeworkm.../case_study.pdf
E Ofek, R Laufer - HBS Case, 2006 - homeworkmarket.com
... The NAT was in a position to reassess further development plans for Cymbalta. Other early steps
of the NAT in late 1998 and early 1999 included an epidemiological study of depression
comorbidities and preliminary market research with physicians to capture the current ...

Repurposing with a difference
http://www.resoundin...repurposing.pdf
MS Boguski, KD Mandl, VP Sukhatme - Science, 2009 - resoundinghealth.com
... Duloxetine (Cymbalta) was also developed to treat depression, but was hypothesized— based
on mechanism of action, not serendip ... opportunities to bring worldwide human resources and
data to bear on biomedical research problems. ... apparent during their development or use ...

#2 FiveNotions

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Posted 27 June 2014 - 11:16 AM

Getting to Yes: corporate power and the creation of a pharmaceutical blockbuster
Discussion of Eli Lilly's antidepressant development process, from Prozac to cymbalta and beyond....
http://www.academia....cal_Blockbuster

#3 thismoment

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Posted 27 June 2014 - 11:24 AM

If Knox Ricksen has learned anything from viewing this website it's that they need to hire FiveNotions right away. Her own office with a view; six figures.


#4 FiveNotions

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Posted 27 June 2014 - 11:41 AM

Thanks, TM! ;-)

Now, back to our regularly scheduled program....

Meet BRETT L. SCHMIDLI, one of the two founders and drug development leaders of Eli Lilly's cross-functional "New Antidepressant Team" (NAT), which was formed to find successor drugs to Prozac..... And whose efforts directly spawned Cymbalta......look at his education and career history....does it inspire confidence in the drug that has poisoned us?

http://www.kelley.iu...V (19Aug09).pdf

Meet Mark Demitrack, the other co-founder of Lilly's NAT and developer of Cymbalta.....my, look what he's involved in now.....

http://www.neuroneti...eam/mdemitrack/

#5 fishinghat

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Posted 27 June 2014 - 12:00 PM

That is interesting That BS in Chemical Engineering, in our local Universities only require 2 coarses in chemistry and the rest in engineering. What got him his job is the MBA (Masters of Business Administration). That is the training ground of CEOs and other leaders in how to be efficient in business with little focus on ethics or morality in most Universities.


#6 FiveNotions

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Posted 27 June 2014 - 12:11 PM

Here's another Cymbalta development "gem"...

3/4/2004

4 subjects challenge Lilly over drug trial
Outside overseer says he found no indication that suicide victim was depressed.
http://www.indystar....7-7202-092.html



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