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In Other Words It's A Crap Shoot [Trajectories Of Depression Severity In Clinical Trials Of Duloxetine (Cymbalta)]


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#1 BelaLugosisDad

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Posted 29 August 2014 - 11:43 AM

Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration

http://www.ncbi.nlm....08/?tool=pubmed

 

Trajectories of Depression Severity in Clinical Trials of Duloxetine

 

http://archpsyc.jama...ticleid=1107437

 

" Most patients treated with serotonergic antidepressants showed a clinical trajectory over time that is superior to that of placebo-treated patients. However, some patients receiving these medications did more poorly than patients receiving placebo. These data highlight the importance of ongoing monitoring of medication risks and benefits during serotonergic antidepressant treatment. They should further stimulate the search for biomarkers or other predictors of responder status in guiding antidepressant treatment."


#2 FiveNotions

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Posted 30 August 2014 - 11:52 AM

Very interesting articles, BLG ... shows that this information has been "out there" for years ... but because it's buried in research articles that the "general public" doesn't have access to (and wouldn't read if they did), docs/pharma go right ahead pushing their own agenda ... and being believed ...



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