To give a little bit of background about me, i started taking duloxetine 12 years ago for depression. Later came to know that PCOS triggered it.
In short, i have been on 80 mg (asian version, 40mg/twice a day, for the past 12 years. Just kept taking it religiously .
I put on 40 pounds immediately in 3 months 12 years ago. I associated it with PCOS, but then even on a very low carb diet, i could never lose more than 10 pounds. The weight gain kept on increasing. I reached 80 pounds (the highest . This was 10 months ago. Since then i have been trying to reduce unsuccessfully.
3 months ago, i started intermittent fasting. One meal a day between 6-8pm. Automatically without realising i cut my dose in half (40mg). The initial 7 days were hard (i ate a lot of eggs to supplement for protein in that one meal), but i'm happy to say that after a week, i had no brain zaps, no migraines.
Now i'm at 40mg for the past 3 months.