Jump to content



Photo

Please Help - Horrible Thoughts


  • Please log in to reply
284 replies to this topic

#271 juli

juli

    Good Friend

  • Site Supporter
  • 138 posts

Posted 25 September 2018 - 10:25 AM

I was just thinking to myself that I am just now starting to feel pretty normal.  It's the kind of thing where I was consistently feeling better but not back to my pre-cold turkey self.

 

I can even have a cup of coffee in the morning without regretting it all day :)

 

I look back on the past year and just can't believe that a little pill could put me through all that misery.

 

I am still on my Lexapro and am not even thinking about touching it.  Just want to feel good and normal for a while.


#272 EBB

EBB

    Good Friend

  • Site Supporter
  • 116 posts
  • LocationDenver, CO

Posted 25 September 2018 - 10:31 AM

THanks FH and Juli.  Hmm.  Lexapro seemed to give her some improvement up to 5mg.  She is taking a total of 200mg of Hydroxyzine over a 24 hr period.  She had taken clonidine before but it was better without it.  Maybe we should try it again.  We have some leftovers somewhere...  As for Xanax, her prescriber is reluctant to give her more benzos as she is already taking 2.5mg per day of Ativan.  But I want it to be Friday NOW so we can see if the neurofeedback will help her.  Thanks for the advice, as always.  You all are the best!


#273 fishinghat

fishinghat

    God-like

  • Active Members
  • PipPipPipPipPipPipPipPip
  • 9,106 posts
  • LocationMissouri

Posted 25 September 2018 - 11:35 AM

Take her bp a couple of times and lket me know what she is running for bp. Do NOT try any of the items below before we see what her bp is.

Maximum dose on the hydroxyzine is 400 mg per day but 200 is a standard dose. IF you want to find out if an increased dose will help try 100 mg the next time it is due.  and see if that brings improvement. Do not exceed 200 mg in a day though or you will run out of tablets.
 
If you try the Clonidine then try 0.1 mg twice a day.
 
Please only try one of these at a time so we can see how they work and by all means keep me posted.
 
I will watch for the bp info.

#274 fishinghat

fishinghat

    God-like

  • Active Members
  • PipPipPipPipPipPipPipPip
  • 9,106 posts
  • LocationMissouri

Posted 25 September 2018 - 11:37 AM

Juli, that is great. Are you planning on weaning of the Lexapro at some time?

#275 juli

juli

    Good Friend

  • Site Supporter
  • 138 posts

Posted 25 September 2018 - 11:58 AM

yes i will at some point in time but not sure when that will be.


#276 EBB

EBB

    Good Friend

  • Site Supporter
  • 116 posts
  • LocationDenver, CO

Posted 11 November 2018 - 01:23 AM

Hey this is Chris.  It's been a while since we posted, sorry for the silence.  We're stuck.  EBB has made slow progress up until a couple weeks ago.  She tested positive for a parasite (cryptosporidium parvum) and was advised to take Alinea for it.  After the first course (3 days) she was feeling pretty horrible, but she was encouraged to take another course because it doesn't always completely get rid of it.  She finished the second course 6 days ago and is still feeling totally miserable.  We saw her DO and she suggested we try the 5HTP again.  Didn't help.  She tried more hydroxyzine a while back, and that had no effect at all.  She's been reluctant to increase the Lexapro and is at 7.5mg.  Every time she goes up, she feels bad, and seems to get more pronounced the higher she's gone.  She is really at her wit's end, and we need to do something that will help her quickly.  The thing we haven't tried is Seroquel, which has been mentioned quite a bit in this thread.  I think Juli said it helped immediately but didn't last.  Any thoughts on this?


#277 fishinghat

fishinghat

    God-like

  • Active Members
  • PipPipPipPipPipPipPipPip
  • 9,106 posts
  • LocationMissouri

Posted 11 November 2018 - 06:28 AM

Sorry to hear of the issues she is having.

I did find this.

"7.1 Highly Protein Bound Drugs with Narrow Therapeutic Indices
Tizoxanide (the active metabolite of nitazoxanide) is highly bound to plasma protein (>99.9%). Therefore, monitor for adverse reactions when administering nitazoxanide concurrently with other highly plasma protein-bound drugs with narrow therapeutic indices, as competition for binding sites may occur (e.g., warfarin)."

"Distribution
In plasma, more than 99% of tizoxanide is bound to proteins."
https://dailymed.nlm...54-00144ff88e88

"Duloxetine is highly bound (>90%) to proteins in human plasma, binding primarily to albumin and α1-acid glycoprotein."
https://www.accessda...s011s013lbl.pdf

Cymbalta is a drug that is highly bonded to proteins and therefore would compete with the Aliniea for binding with proteins in the blood. This would reduce the amount of available Cymbalta in the blood and cause an increase in withdrawal symptoms.

I don't know if this helps any but might explain why she fells worse.

Seroquel, clonidine and of course benzos which have their own issues. I can't really think of anything else. Oh, how about L-theanine? Have you tried that?

#278 gail

gail

    God-like

  • Site Supporter
  • 4,923 posts
  • LocationSherbrooke, PQ
  • why_joining:
    5 months on cymbalta, scary side effects, never felt good.
    Needed understanding and support, and a place where I was not alone. To read others stories and realizing that I was not the only one going through all that crap.
    In hope that one day, I can return the favors in some kind of way.

Posted 11 November 2018 - 07:44 AM

Hi Chris,

So sorry for Ebb. This has been going on for quite a while.

Seroquel, that was me that mentioned it.

Story: I stopped Cymbalta then waited seven months. Then I went on Seroquel 150 xr taken before bed. I was sleepy when I woke up but felt completely normal. That lasted for one month, one month of feeling so normal. Then, it pooped, it stopped working. Then it was trial and error for many years.

Worth a try, doesn't mean it does that to everyone. Best of luck!

#279 EBB

EBB

    Good Friend

  • Site Supporter
  • 116 posts
  • LocationDenver, CO

Posted 12 November 2018 - 11:33 AM

Thanks Gail and FH.  The competing Alinea makes sense to me.  She had an improved day yesterday and I'm hopeful it is the Alinea getting out of her system.  She was also low on zinc so she took a very small amount from a cold-eeze lozenge (so she doesn't get a copper dump) and that might have contributed to the improvement too.  Fingers crossed.  Gail, the Seroquel must have been very frustrating getting your hopes up and then suddenly not working!  We'll keep Seroquel in our back pocket.


#280 gail

gail

    God-like

  • Site Supporter
  • 4,923 posts
  • LocationSherbrooke, PQ
  • why_joining:
    5 months on cymbalta, scary side effects, never felt good.
    Needed understanding and support, and a place where I was not alone. To read others stories and realizing that I was not the only one going through all that crap.
    In hope that one day, I can return the favors in some kind of way.

Posted 12 November 2018 - 01:13 PM

Hi Chris, hope Ebb is getting better as the alinea gets out of her system.

Oh yes Chris, after 30 days of well being, it was a huge disappointment. So huge.

#281 EBB

EBB

    Good Friend

  • Site Supporter
  • 116 posts
  • LocationDenver, CO

Posted 18 December 2018 - 01:06 AM

Hey it's Chris.  One thing that we're wondering about is Lamictal.  I know there are a lot of false positive diagnoses of bipolar with Cymbalta withdrawal, but some of the description of Bipolar II seems to resonate for her.  Lamictal is indicated as a strong choice for it, and her genetic tests show that there are no contraindications for her.  There are scary side effects for a very small percentage of people.  I see in the summary some stuff about withdrawal when coming off of it too fast.  Just wondering if you've come across anyone who has had a good or bad experience with it in alleviating withdrawal symptoms.  She has COMT gene variant, and you mentioned Lamictal has been used for helping this.  What do you think?  Is it worth trying?


#282 fishinghat

fishinghat

    God-like

  • Active Members
  • PipPipPipPipPipPipPipPip
  • 9,106 posts
  • LocationMissouri

Posted 18 December 2018 - 10:40 AM

A lot of people had good experiences in using it to handle Cymbalta withdrawal. There was a couple of comments about excessive habits while on both together. Spending lots of money and/or drinking lots of alcohol. The degree of withdrawal varies a lot. Some say a few weeks and no issues and others say as bad as Cymbalta. Don't you just love prescription meds?


#283 gardenlady

gardenlady

    Good Friend

  • Active Members
  • PipPipPipPip
  • 102 posts
  • LocationWest Tennessee

Posted 18 December 2018 - 09:25 PM

Chris, It's very common for people who are coming off of psych drugs to be "diagnosed" as bipolar, when in actuality, it's just a withdrawal symptom.  Psychiatrists will inevitably prescribe more drugs (what else do they do?) for nonexistent mental illnesses which are nothing but withdrawal symptoms, therefore, spiraling the person downward into increasingly worsening conditions.  Many people report that after they are through withdrawal, the so-called bipolar symptoms disappear.

 

These so-called diagnoses are really just descriptors, labels that psychiatrists make up and then change, subjectively, as time goes on.  There's nothing objective or scientific about it.  The DSM is a joke...if you do research into how it came into being, you'll see what a laughable publication it is.  Check this out: 

 

https://www.theinner...s-are-diagnosed

https://www.theinner...stic-manual-dsm

 

Just a word of caution.  Don't believe the bipolar diagnosis and the recommendation for additional drugs to fix a condition that is caused only by antidepressant or other psych drug withdrawal.  In such situations, bipolar is a non-existent diagnosis with a so-called "remedy" that will cause only more harm.  When it comes to withdrawal or psych drug adverse effects, psychiatrists are delusional and in denial and, therefore, chase shadows by unnecessary and harmful prescribing.  Don't let your wife be yet another unsuspecting victim of their willful ignorance. 


#284 EBB

EBB

    Good Friend

  • Site Supporter
  • 116 posts
  • LocationDenver, CO

Posted 19 December 2018 - 01:43 PM

Thanks FH and GL.  I would definitely rather not add more meds with their butterfly effect of more issues.  We are waiting to see how she does before we jump into this stuff.  It's been pretty rough for her, and we just need the next step in our plan should we need it.


#285 gardenlady

gardenlady

    Good Friend

  • Active Members
  • PipPipPipPip
  • 102 posts
  • LocationWest Tennessee

Posted 19 December 2018 - 05:19 PM

Chris, Lamictal can be a very dangerous drug.  Research it thoroughly and read about Stevens Johnson Syndrome that it's associated with.  Back when I was naive and believed that psychiatrists knew what they were doing, I stupidly follow the advice of one who put me on Lamicatal because she was clueless that I was in benzo withdrawal and thought I had a mental illness.  I had to rush to the ER due to a rash that was eerily similar that of Stevens Johnson Syndrome and was told to stop it immediately.  It can be a disfiguring and fatal condition.  

 

It was after that that I became educated about how ignorant doctors are about psych meds and withdrawal from them.  I would never again go to a psychiatrist or take any of their brain-damaging poisonous potions.  

 

Unfortunately it may take a very long time for your wife's brain to heal from the damage caused by the drugs she has already taken.  Some heal in 6 months or so, but others take 5-7 years or even longer.  There's no way to predict.  But adding more drugs is only pouring gasoline on the fire and increasing the already lengthy healing time. 





0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users