Natural Treatments for Cymbalta Withdrawal Symptoms (cont.)http://www.cymbaltaw...tion#entry37106
Kratom information and discussion.
Kratom is a tropical evergreen tree in the coffee family native to Southeast Asia.
As of 2018, little is known of kratom's worth or safety as a therapeutic agent, since research into its use has been of poor quality. In February 2018, the Food and Drug Administration (FDA) stated that there is no evidence kratom is safe or effective for treating any condition. Some people take it for managing chronic pain, for treating opioid withdrawal symptoms, or – more recently – for recreational purposes. Onset of effects typically begins within 5 to 10 minutes and lasts 2 to 5 hours.
Common minor side effects may include nausea, vomiting, and constipation. More severe side effects may include respiratory depression (decreased breathing), seizure, addiction, and psychosis. Other side effects may include high heart rate and blood pressure, trouble sleeping, and, rarely, liver toxicity. When use is stopped, withdrawal symptoms may occur. Deaths have occurred with kratom both by itself and mixed with other substances. Between 2011 and 2017, 44 kratom-related deaths occurred, only one of which involved kratom alone. Nine kratom-related deaths occurred in Sweden in 2011 and 2012, all involving a mixture of kratom with a prescription opioid analgesic.
The U.S. Drug Enforcement Administration has issued a "Drugs of Abuse Resource Guide", which states "Kratom is not controlled under the Federal Controlled Substances Act; however, there may be some State regulations or prohibitions against the possession and use of kratom. Alabama, for example, outlawed the use and possession of kratom in May 2016, and all stores in Alabama were ordered to immediately remove all kratom products from their shelves. In addition, DEA has listed kratom as a Drug and Chemical of Concern." There is no FDA-approved medical use for kratom in the United States.
On June 9, 2015, the Food and Drug Administration (FDA) announced an import alert for kratom, issuing guidance that shipments are to be seized without physical examination from several vendors listed due to concerns that there is no evidence that Kratom does not pose an unnecessary risk of illness or injury, further stating that "[C]onsumption of kratom can lead to a number of health impacts, including respiratory depression, nervousness, agitation, aggression, sleeplessness, hallucinations, delusions, tremors, loss of libido, constipation, skin hyperpigmentation, nausea, vomiting, and severe withdrawal signs and symptoms."(Wiki)http://www.ncbi.nlm....pubmed/20798544
Seizures and coma;http://www.ncbi.nlm....pubmed/20411370
The more I read the more it sounds like a drug similar to the alkoids in opium.
Great caution should be exercised before use of this product. It reacts with the same receptors as opium. Immediate deaths have occured with taking it. Most commercial (internet) products contain codiene, pseudoephrine, caffiene and other stimulants with the Kratom. Some foreign countries are using this like you would an opiod pain killer. It is addictive and you can build up tolerance to it.http://www.ncbi.nlm....pubmed/24325774http://www.ncbi.nlm....pubmed/23846544http://www.ncbi.nlm....pubmed/23212430http://www.ncbi.nlm....pubmed/23206666http://www.ncbi.nlm....pubmed/23082895http://www.ncbi.nlm....pubmed/22018854
Fishinghat - A caution for those who use or are considering using valerian root. It greatly slows down the bodies ability to process and eliminate benzos. This allows the benzos to build to very high values in the body. Caution should be used when taking the two at the same time.
Fivenotions - Ditto to the valerian caution.....I tried it as tea....wasn't using benzos, but it whacked me out somehow....a tip I got from Fishinghat is to start whatever it is you're trying....amino, herb, etc....in very small amounts/doses....and work up gradually....
Boot2 - i found if i combined chocolate (i am using unsweetened health food store kind now) and valerian- it feels like i am almost normal again...thought i;d pass that along.
LadyNancy - I had a reaction to valerian but then that is nothing new for me.
RussellSprout - The valerian/mag combo (when I remember to do both) doesn't act like a sleeping pill or anything of that sort, but it does physically relax me so I can drift to sleep more easily. Unfortunately, the valerian smells like death.
Hornet - I too am enjoying the dreams. Additionally, I have been taking Valerian root to help sleep and it exacerbates the dreams.
brzghoff - valerian works for some, gives me a headache.
jillybean - I also use valerian root (from puritan's pride) 450 mg capsules 1 capsule late afternoon and 1 before bed. This is considered nature's valium and though it does not make me drowsy I do feel it is helping with anxiety. I missed the late afternoon dose yesterday and had one hell of a panic attack. I won't do that again.
Albergo - Made things worse: Valerian root (really bad reaction - BIG WARNING), benzodiazepines (clonozepam .5mg, took 1-2 weeks to recover from),
Around 20 members mention taking valerian, especially in their SleepyTime Tea. I would estimate around 60% said it helped with around 40% saying no. Several had bad reactions/interactions with it.
Drug.com list 581 drug interactions for Valerian, including sleep aides, benzos, cold medicines, and more.
FiveNotions - Instead of valerian, I use damiana tea...from the fresh herb.....but a caution there....it can lower blood pressure, esp. Systolic....that's a benefit for me, but not if you already run low or take meds for bp.....
Fishinghat - Interesting. I couldn't find anything about damiana (Turnera diffusa) treating anxiety in the medical journals. But I found several articles on Turnera aphrodisiac being as effective as diazepam. The active ingredient on Turnera aphrodesiacis, Apigenin, which works on benzo receptors. (see reference below )
Kumar, S; Madaan, R; Sharma, A (2008), "Pharmacological evaluation of Bioactive Principle of Turnera aphrodisiaca", Indian Journal of Pharmaceutical Sciences, 70: 740–4, doi:10.4103/0250-474X.49095, PMC 3040867 , PMID 21369434
Apigenin is a potent inhibitor of CYP2C9 an enzyme responsible for the metabolism of many pharmaceutical drugs in the body. Ingestion of this substance would significantly reduce the absorption of medicines and supplements absorbed via the CYP2C9 enzyme. It also effects opiod and adenosine receptors as well. It can increase testosterone levels, decreases cortisol levels, (See reference below for source references).https://examine.com/...ments/apigenin/
Many references state that Turnera diffusa and T. aphrodisiaca are generally regarded as the same plant in herbal commerce. This may explain why some supplements have a better reputation than others. Many mention that damiana is also an aphrodesiac but again this is not damianas but Turnera aphrodisiac.
The article here talks about the anti-anxiety properties of damianas in research BUT the research they quote was done on Turnera aphrodesiac not Turnera diffusa (damianas).
Jujube (also called San Zao Ren) (Genera Ziziphus)
FH - San Zao Ren is the same thing as Jujube. It does have anxiolytic effects but can also reduce bp so please monitor carefully.
Geebers - She gave me an herbal powder called San Zao Ren (Chao). This is to help with the anxiety and sleep.https://www.ncbi.nlm...pubmed/19260286
The alcohol extracts of Semen Ziziphi Spinosae have the anti-anxiety effects instinctively. Its mechanism may be related to increasing the GABA and expression of GABAAR1 and reducing the Glu and expression of NMDAR1.https://www.ncbi.nlm...pubmed/19101585
It is concluded that sanjoinine A may have anxiolytic-like effects in the elevated plus-maze, hole-board test and open field test, and these effects may be mediated by GABAergic transmission.https://www.ncbi.nlm...pubmed/19505549
ZE (jujube) with the 5-HT(1B) (serotonin) receptor.https://www.ncbi.nlm...pubmed/10996283https://www.ncbi.nlm...pubmed/14531016
All the above mention anxiolytic effects.https://examine.com/...iziphus-jujuba/
Traditional usage of Jujube is taking 50g of the fruits (20 individual 2-2.5cm diameter fruits) and doing a hot water extract, either a soup of a beverage.
There currently is not enough evidence in humans to establish an effective oral dose of Zizyphus Jujube supplements but estimating from animal studies finding benefits with 500mg/kg for anxiety reduction, an estimated human dose would be:
⦁ 5,500 mg for a 150lb person
⦁ 7,300 mg for a 200lb person
⦁ 9,000 mg for a 250lb person
The seeds of Ziziphus jujube have been implicated in reducing anxiety, in accordance with their traditional usage. Oral administration of 0.5, 1, and 2g/kg of the ethanolic seed extract in mice was able to exert anxiolytic effects, and although it was equally effective as Buspirone and Diazepam (2mg/kg and 1mg/kg, respectively) at a black and white test (anxiety model) at 500mg/kg, it appeared to become less potent at anxiolysis at 1 and 2g/kg while becoming more sedative in nature.
Highly regarded as a sedative in traditional chinese medicine with minimal Western trials on its efficacy, it appears to induce sedation in a relatively dose dependent manner and is synergistic with 5-HTP in this regard.
Good for constipation. May be acutely anti-fertility, but there is limited evidence to support this notion.
Above reference contains support references.
As no human toxicity tests have been performed care should be used when taking this supplement.
NAC - N-acetylcysteine - Strong antioxidant.https://www.ncbi.nlm...pubmed/18534556
NAC appears a safe and effective augmentation strategy for depressive symptoms in bipolar disorder.https://www.ncbi.nlm...pubmed/25004186
the study provides only limited support for the role of NAC as a novel adjunctive therapy for MDD.https://www.ncbi.nlm...pubmed/21719110
These open label data demonstrate a robust decrement in depression scores with NAC treatmenthttps://www.ncbi.nlm...pubmed/22891797
There were no significant between-group differences in recurrence or symptomatic outcomes during the maintenance phase of the trial;https://www.ncbi.nlm...pubmed/27725170
The anxiolytic effects of NAC were comparable to diazepam.
Freeme - I have been taking milk thistle to detox the liver and zertex. I put benadryl spray on my arms at night. I am taking also x3 NAC which cleanses the liver too. These both will calm down my itchy to nothing.
3 members reported a positive experience with this product.
Rockstar Energy Drink
4 members mention using it for dehydration, brain zaps and fog as well as an energy drink,https://www.walgreen...6020233-product
The world's most powerful energy drink. Enhanced with the potent herbal blend of guarana, ginkgo, ginseng and milk thistle. Scientifically formulated to provide an incredible energy boost for those who lead active and exhausting lifestyles-from athletes to rock stars. Enjoy this fully refreshing, lightly carbonated beverage super chilled. Double strength & size.
Not Recommended For Children, pregnant or nursing women Or Those Sensitive To Caffeine.https://en.wikipedia...drink)#Contents
Rockstar products in the US have two levels of caffeine content - either 10 mg of caffeine per ounce, or 15 mg of caffeine per ounce. Rockstar Energy Drink Original contains 160 mg of caffeine per 16 ounce can, while the Rockstar Punched energy drink contain 360 mg of caffeine per 24 ounce can.
Besides caffeine and sugar, Rockstar Energy Drink contains a variety of herbs, including panax ginseng, ginko bilobe, milk thistle extract, and guarana seed. The amount of guarana used to be higher, but "after being criticized for including guarana once health concerns about the herb were publicized, the amount in the drink was significantly reduced." It also includes 1000 mg of tqurine.
Rockstar can cause jitteriness, head aches, anxiety, and high blood sugar levels. If mixed with alcohol it may also mask the level of alcohol intoxification.https://www.ncbi.nlm...les/PMC5015039/
a study in which blood pressure and heart rate responses to a sugar-sweetened ED (Rockstar, Rockstar, Inc.; 240 mg caffeine and ∼62 g sugar) resulted in significantly elevated blood pressure values (systolic blood pressure: +6.6 mm Hg; diastolic blood pressure: +4.2 mm Hg) compared with a sugar-matched placebo.
3 members found Vicks Vapor Rub calming.
TOC - At night I put vicks on my sinus areas, it soothes me and calms me.https://vicks.com/en...opical-ointment
Regular:Camphor (synthetic) 4.8% (Cough suppressant and topical analgesic)
Eucalyptus oil 1.2% (Cough suppressant)
Menthol 2.6% (Cough suppressant and topical analgesic)
Some versions contain lavendar oil which has been found to help releive anxiety.
Lion's Mane Mushroom
(AKA Yamabushitake or H. erinaceum )https://www.ncbi.nlm...pubmed/24506286
Lion's Mane Mushroom (LMM) contains Vitamin B12.https://www.ncbi.nlm...pubmed/23510212
Daily oral administration of H. erinaceus could promote the regeneration of injured rat peroneal nerve in the early stage of recovery.https://www.ncbi.nlm...pubmed/27481156
Anti-inflammatory, a protective agent in the treatment of IBDs (inflammatory bowel disease).https://www.ncbi.nlm...pubmed/29199560
This study demonstrates novel characteristics of H. erinaceus in reducing nociceptive (pain) behavior and blocking the functional activity of P2R (calcium binding receptors).https://www.ncbi.nlm...les/PMC5237458/
In wild-type mice the oral supplementation with H. erinaceus induces, in behaviour test, a significant improvement in the recognition memory and, in hippocampal slices, an increase in spontaneous and evoked excitatory synaptic current in mossy fiber-CA3 synapse. In conclusion, we have produced a series of findings in support of the concept that H. erinaceus induces a boost effect onto neuronal functions also in nonpathological conditions.https://www.ncbi.nlm...les/PMC5133811/
Our findings provide experimental evidence that HE (H. erinaceus) may provide neuroprotective candidates for treating or preventing neurodegenerative diseases.https://www.ncbi.nlm...les/PMC4895996/
Our results demonstrate that HEPS exhibit antioxidant and neuroprotective effects on Aβ-induced neurotoxicity in neurons.https://examine.com/.../yamabushitake/
Yamabushitake, known as the Lion's Mane Mushroom, is a dietary mushroom that can be a supplement.
As the water soluble extract seems to be less potent than other fractions, it may be best to take Yamabushitake with meals if in supplemental form.
If itchy skin occurs, this may be related to an increase in Nerve Growth Factor and unless accompanied by signs of allergy should be benign.
Currently, the only human study has used an oral dose of 1,000mg Yamabushitake (96% purity extract) thrice daily for a cumulative total of 3,000mg extract. While it is unknown if this is the optimal dose or not, it appeared to be effective.
Yamabushitake has been noted to increase mRNA expression of nerve-growth factor (NGF) (Nerve growth factor is primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target nerve cells.) in isolated astrocytes to around 5-fold that of control at 100-150ug/mL of the ethanolic extract in a concentration dependent manner, with no efficacy noted in the water extract
An increase in NGF mRNA has been detected in the hippocampus, but not cortex, of mice given 5% of the diet as yamabushitake for a period of seven days to around 1.3-fold of control. (Note - Interesting as Cymbalta heavily afects the hippocampus).
Neuronal excitability from glutamic acid appears to be attenuated in the presence of yamabushitake extracts.
Anxiety and Depressive symptoms have also been reduced in humans fed 2g of Yamabushitake, via cookies, over the course of 4 weeks. There was a significant difference between groups on the measurements of concentration and irritability, favoring the Yamabushitake group. Nagano M, et al. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. (2010)
Yamabushitake may act as a PPARα agonist and reduce triglycerides without any apparent effect on cholesterol.
Although both the hot water and ethanolic extracts have been found inactive on cholesterol and HDL-C, an extract derived from the mycelium of yamabushitake (ethanolic extract which was then lyophilized) appeared to reduce LDL by 45.5% and improve HDL-C by 31.1% when taken at an oral dose of 200mg/kg with 50mg/kg also being somewhat active
There has been one case study of a 63 year old man who suffered acute respiratory failure, and the excess lymphocytes in his lungs showed high reactivity to Yamabushitake daily for 4 months in dosages commonly bought. The connection between the two, when rated, is seen as a 'probably' connectionhttps://nootropicsex...e/#dosage-notes
Dosing of Lion’s Mane Mushroom depends on the strength of the extract. It’s available in capsule or powder form.
For Lion’s Mane 10:1 extract (30% polysaccharide), daily dosage is 500 – 1,000 mg taken 1 to 3 times per day.
Other retail extract dosage of Lion’s Mane ranges from 300 mg to 3000 mg dosed 1 – 3 times per day. Check the label and see what the manufacturer recommends. And when first using the supplement, start with the lowest dose and see how your body reacts.
Start at 500 mg per day and see how it works for you. If you don’t experience a benefit, boost Lion’s Mane in small increments of 250 mg per day until you notice an improvement.
Lion’s Mane Mushroom is non-toxic and considered very safe. So there are very few side effects reported.
Some neurohackers report itchy skin from higher doses. Likely attributable to a boost in Nerve Growth Factor.
Lion’s Mane has been tested in animals showing no side effects or toxicity even up to 5 grams per kilogram.https://www.cabdirec...act/20103302738
Our results show that H. erinaceum intake has the possibility to reduce depression and anxiety.
Erinacine A, isolated from the cultured mycelia of H. erinaceum, the main representative of this compounds group, has a strong enhancing effect on NGF synthesis, much stronger than epinephrine. Furthermore, this compound increases catecholamine and NGF content in the central nervous system of rats.
Erinacines and hericenons reduce anxiety as well as depression. For an accurate understanding of the overall mechanism of H. erinaceus diterpenoids action it requires additional clinical studies with physiological markers, such as hormones, or more profounded studies of autonomic nervous activityhttps://www.thefreel...on.-a0430893147
Summary of the antianxiety/antidepressive effects of components of H. erinaceus.
BK Yang et al., “Hypolipidemic effect of an Exo-biopolymer produced from a submerged mycelial culture of Hericium erinaceus," Bioscience, Biotechnology, and Biochemistry, vol. 67, no. 6 (June 2003): 1292–1298.
A cell wall polysaccharide produced by a special, submerged culture of lion’s mane mushroom was found in an animal study to lower cholesterol by 32%, LDL cholesterol by 45.4%, and triglycerides by 34.3%, and to raise the “good” HDL cholesterol by 31%.9 The researchers proposed that the mushroom’s constituents helped to lower cholesterol production via the hepatic HMG-CoA reductase pathway, reducing the amount of this enzyme by 20%.
Sweet Fennel Tea
Numerous members used Sweet Fennel Tea to improve sleep and to treat edema.
Drinking fennel tea may increase your skin's sensitivity to sunlight, notes Drugs.com.
People who have a known allergy to carrots, celery or mugwort are at an increased risk of developing an allergic reaction upon exposure to fennel. Symptoms associated with an allergic reaction may be life-threatening and include facial swelling, difficulty swallowing or breathing, hives or dizziness. Seek prompt care from your medical provider if you exhibit any of these side effects after drinking a cup of fennel tea.
Consumption of fennel tea should also be avoided by people with a personal history of a seizure disorder, such as epilepsy, as this herbal treatment may increase your risk of experiencing seizures.
Do not consume fennel if you are also taking birth control pills or any estrogen-based therapeutic drugs, as fennel may reduce the efficacy of such drugs. Concomitant use of fennel tea and ciprofloxacin or tamoxifen should also be avoided. Fennel may make it harder for your body to properly absorb these medications.
St. John's wort
Classified as a ssri.
Special Precautions & Warnings:
Pregnancy and breast-feeding: St. John's wort is POSSIBLY UNSAFE when taken by mouth during pregnancy. There is some evidence that it can cause birth defects in unborn rats. No one yet knows whether it has the same effect in unborn humans. Nursing infants of mothers who take St. John's wort can experience colic, drowsiness, and listlessness. Until more is known, do not use St. John's wort if you are pregnant or breast-feeding.
Children: St. John's work is POSSIBLY SAFE when taken by mouth for up to 8 weeks in children 6-17 years-old.
Alzheimer's disease: There is concern that St. John's wort might contribute to dementia in people with Alzheimer's disease.
Anesthesia: Use of anesthesia in people who have used St. John's wort for 6 months may lead to serious heart complications during surgery. Stop using St. John's wort at least 2 weeks before a scheduled surgery.
Attention deficit-hyperactivity disorder (ADHD): There is some concern that St. John's wort might worsen symptoms of ADHD, especially in people taking the medication methylphenidate for ADHD. Until more is known, don't use St. John's wort if you are taking methylphenidate.
Bipolar disorder: People with bipolar disorder cycle between depression and mania, a state marked by excessive physical activity and impulsive behavior. St. John's wort can bring on mania in these individuals and can also speed up the cycling between depression and mania.
Depression: In people with major depression, St. John's wort might bring on mania, a state marked by excessive physical activity and impulsive behavior.
Infertility: There are some concerns that St. John's wort might interfere with conceiving a child. If you are trying to conceive, don't use St. John's wort, especially if you have known fertility problems.
Schizophrenia: St. John's wort might bring on psychosis in some people with schizophrenia.
Surgery: St. John's wort might affect serotonin levels in the brain and as a result interfere with surgical procedures. Stop using St. John's wort at least two weeks before a scheduled surgery.
Several animal and human investigations suggest anxiolytic, mood stabilizer, sedative, analgesic, and anticonvulsive and neuroprotective properties for lavender.
The main constituents of lavender are linalool, linalyl acetate, 1,8-cineole B-ocimene, terpinen-4-ol, and camphor. However, the relative level of each of these constituents varies in different species
Presenting series of 78 patients, who have been using camphor â€“based substances (CBS) from more than 5 years in topical and oral forms. All of these patients were dependent on these substances for reliving symptoms of headache, insomnia and even seizures. Patients have symptomatic symptoms on their withdrawal. 6 month withdrawal was 67% with 16% relapse of usage of CBS. Question arises, Does camphor makes the patient dependent? Does camphor results in permanent neural tissue damage
The present findings suggest that inhalation of 1,8-cineole may be used to relieve anxiety before, during, and after various operations.
No other research articles found.
No research articles found to show that Menthol helps treat anxiety or depression.
(Withania somnifera )https://www.ncbi.nlm...pubmed/25405876
All five studies concluded that WS intervention resulted in greater score improvements (significantly in most cases) than placebo in outcomes on anxiety or stress scales.https://www.ncbi.nlm...pubmed/26068424
Our results provide evidence indicating that key constituents in WS may have an important role in the development of pharmacological treatments for neurological disorders associated with GABAergic signaling dysfunction such as general anxiety disorders, sleep disturbances, muscle spasms, and seizures.https://www.ncbi.nlm...pubmed/19718255
300 mg twice a day.
Final BAI scores (anxiety test) decreased by 56.5% in the Ashwagandha group. Significant differences between groups were also observed in mental health, concentration, fatigue, social functioning, vitality, and overall quality of life with the Ashwagandha group exhibiting greater clinical benefit. No serious adverse reactions were observed in either group.http://www.ncbi.nlm....pubmed/24497737
250 mg 2x/dayhttp://www.ncbi.nlm....pubmed/24330893
500 mg/day for bipolar, effective.http://www.ncbi.nlm....pubmed/23439798
Each capsule contained 300 mg of high-concentration full-spectrum extract from the root of the Ashwagandha plant. Each person took 2 capsules a day. The treatment group that was given the high-concentration full-spectrum Ashwagandha root extract exhibited a significant reduction in scores on all the stress-assessment scales on Day 60, relative to the placebo group. The serum cortisol levels were substantially reduced in the Ashwagandha group, relative to the placebo group. No serious adverse events were reported.http://www.ncbi.nlm....pubmed/22546655
W. somnifera extract is effective in treating obsessive compulsive disorderhttps://www.ncbi.nlm...pubmed/18697607
The results suggest the protective effect of WS in the management of ethanol (alcohol)withdrawal reactions.https://www.ncbi.nlm...pubmed/17585686
Preliminary results suggest that Withania root extract can be used in the management sleep loss and associated oxidative stress.http://www.ncbi.nlm....pubmed/19363747
Effective for anxietyhttp://www.ncbi.nlm....pubmed/11194174
WSG also exhibited an antidepressant effect, comparable with that induced by imipramine in the 'behavioural despair' and 'learned helplessness' tests. The investigations support the use of WS as a mood stabilizer in clinical conditions of anxiety and depressionhttp://www.ncbi.nlm....les/PMC3252722/
It has a Cognition Promoting Effect and was useful in children with memory deficit and in old age people loss of memory. It was also found useful in neurodegenerative diseases such as Parkinson's, Huntington's and Alzeimer's diseases. It has GABA mimetic effect and was shown to promote formation of dendrites. It has anxiolytic effect and improves energy levels and mitochondrial health. It is an anti-inflammatory and anti-arthritic agent and was found useful in clinical cases of Rheumatoid and Osteoarthritis.http://www.ncbi.nlm....les/PMC3487234/
1,250 mg/day × 10 days
All volunteers tolerated WS without any adverse event.
Safety and side effectshttp://www.ncbi.nlm....les/PMC2958355/
This product is comparative to lorazepam in its ability to control anxiety. That is impressive.https://www.ncbi.nlm...les/PMC2958355/
250 mg twice a day.
At 6 weeks, significantly more patients met a priori response criteria in the drug group (88.2%) as compared with the placebo group (50%). The drug was well-tolerated and did not occasion more adverse effects than did placebo. It is concluded that this ethanolic extract of Withania somnifera has useful anxiolytic potential and merits further investigation.https://www.ncbi.nlm...pubmed/28004351
This study provides scientific validation to the anxiolytic, anti-inflammatory and anti-apoptotic properties of ASH-WEX, which may serve as an effective dietary supplement for management of SD induced stress and associated functional impairments.
One member reported taking it during withdrawal and said it was very beneficial.
Brz - ashwagandha update:
had to stop - bummer.
definitely allergic. just like sk8ermama. i couldn't figure out why my allergies hadn't gone away even after the pollen count dropped way down. stopped the ashwagandha and my congestion and headaches subsided. not to mention i had a very tight chest feeling. very uncomfortable. my side effects are not uncommon from what i've learned. i may try again way down the road but now that i'm battling reflux, i don't want to complicate things. i've heard rhodiola is a similar adaptogen, but don't want to introduce anything new into my system right now.