This is an exert from Summary of Cymbalta Withdrawal".
Zantac
Contains Ranitidine is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.
http://www.cymbaltaw...tion#entry66071
Zantac (Ranitidine) For Anxiety And Depression
FiveNotions - I've stumbled onto the discovery that Zantac, which I'd been taking for severe acid reflux, seems to help my post-crapalta anxiety ... did some research, and found a number of old (really old) articles that seem to confirm this ... here's one of the freely available ones …
jimmcg - Now, with a week on the Zantac, I feel much more in control of these feelings. I may wake up worrying about something in the middle of the night, but, unlike before, I can talk myself through it and go back to sleep.
Sparkybird - FYI I some research on Zantac and found it was the source of the depression and anxiety I had this morning. This might help others along te way.
https://www.ehealthm...tac/depression/
54,938 people reported to have side effects when taking Zantac.
Among them, 1,859 people (3.38%) have Depression
https://www.ehealthm...zantac/anxiety/
54,938 people reported to have side effects when taking Zantac.
Among them, 2,370 people (4.31%) have Anxiety
Caution : but be aware that new research is showing that extended use of Zantac, and / or use of the highest dose, may cause liver damage.
https://livertox.nlm.../Ranitidine.htm
http://pmj.bmj.com/c...03/353.full.pdf
Effect of the H2-receptor antagonist ranitidine on depression and anxiety in duodenal ulcer patients
(150 mg twice daily0 In both groups there was a highly significant and progressive decrease in depression and anxiety scores over the 4 weeks of treatment.
https://www.ncbi.nlm.../pubmed/9833631
The H1- and H2-histamine blockers chlorpheniramine and ranitidine show that H1- and H2-receptor antagonists differentially modulate reinforcement and fear-related processes in the NBM and thus, provide the first evidence for a behavioral relevance for the histaminergic innervation of this brain site.
https://www.ncbi.nlm...les/PMC3854398/
H1 but not H2 histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing
As well as...
https://www.ncbi.nlm...pubmed/18275952
https://www.ncbi.nlm...pubmed/17109942
https://www.ncbi.nlm...pubmed/16600315
https://www.ncbi.nlm...pubmed/23535246
https://www.ncbi.nlm...pubmed/22952484
Plus many more....
Drug interactions -
Zantac (Ranitidine) may significantly increase the blood levels of loperamide (Imodium). This can lead to serious and potentially fatal complications such as irregular heart rhythm and cardiac arrest, especially if you use more than the recommended doses of loperamide.
Zantac CAN be taken with Benadryl. They are different types of antihistamines. Drugs.com
