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Posted 02 August 2020 - 11:08 AM
Posted 05 August 2020 - 09:26 AM
Posted 07 August 2020 - 04:17 PM
Posted 09 August 2020 - 05:44 PM
Tryptophan is converted to 5htp which is converted to serotonin which is converted to melatonin during low light conditions. I can find no reference to this reaction going backwards. (eg. melatonin to serotonin).
There is reference to the reverse of daylight stimulating the conversion from melatonin to serotonin, but I cannot find hard evidence of this either. I looked into this when I was taking melatonin. As I am a night owl and my circadian rhythm is already out, I was worried that overdoing the melatonin, coupled with the lack of sunlight might be having a detrimental effect.
But given that too much melatonin can cause depression, it would certainly point to there being no evidence for its conversion back to serotonin - if anything, this points to the opposite.
Posted 13 August 2020 - 12:02 PM
Posted 17 August 2020 - 08:27 AM
Posted 17 August 2020 - 08:52 AM
If melatonin were effecting serotonin it certainly would make any digestive symptoms worse as well. Both Nystatin and melatonin list muscle spasms occurring in around 2% of the cases.
Nightmares are not normally experienced with either med (<0.6%).
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