Jump to content



Photo

Cymbalta And Magnesium


  • Please log in to reply
5 replies to this topic

#1 fishinghat

fishinghat

    Site Partners

  • Active Members
  • PipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPip
  • 12,554 posts
  • LocationMissouri

Posted 18 March 2019 - 05:29 PM

A recent study shows that the taking of Cymbalta with magnesium oxide (an antacid) causes a reduction in blood levels of Cymbalta. This correlates with the reports from ehealthme where the number three reported effect by taking magnesium with Cymbalta is a decreased effect of Cymbalta. This makes one rethink the use of magnesium supplements with the use of Cymbalta and that the combination may make withdrawal worse.

https://www.ncbi.nlm...pubmed/30381673
although the serum duloxetine level was significantly decreased. However, the antidepressant-like effects of a duloxetine reagent were significantly attenuated by the co-administration of magnesium oxide. These results suggest that duloxetine and magnesium oxide directly interact and that such interactions affect the absorption and antidepressant-like effects of duloxetine.



https://www.ehealthm...esium/cymbalta/
< 1 month:
Somnolence (a state of near-sleep, a strong desire for sleep)
Condition ?
Drug ineffective
Neuralgia (pain in one or more nerves)
Dizziness
Diarrhea
Hypoaesthesia (reduced sense of touch or sensation)
Nerve compression
Peripheral swelling
Weight decreased

#2 invalidusername

invalidusername

    Site Partners

  • Site Supporter
  • 5,335 posts
  • LocationKent, UK

Posted 18 March 2019 - 06:37 PM

Yes - and magnesium oxide is in EVERYTHING as it is the cheapest. It is not readily absorbed, but is used in many multi vits and as fillers for a number of other supplements, so watchful on eye on what you are buying.

 

Exactly like I found with my super-absorbant iron... One can never be too careful when mixing any two of anything!!


#3 fishinghat

fishinghat

    Site Partners

  • Active Members
  • PipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPip
  • 12,554 posts
  • LocationMissouri

Posted 19 March 2019 - 08:50 AM

Good point IUN. Going back and considering that many members used magnesium with a wide variety of effects. Most magnesium they used was in the oxalate or chelated forms. It works great for some an made things worse for others. I suspect that the ones that took it during their withdrawal made have been made worse by the magnesium depending on the form it was in and if it decreased Cymbalta levels in the blood. If I get time some day I will research back and see if I can find a pattern.

For now I would consider the use of magnesium during withdrawal suspect.

#4 gail

gail

    Site Partners

  • Site Supporter
  • 6,016 posts
  • LocationSherbrooke, PQ
  • why_joining:
    5 months on cymbalta, scary side effects, to get help and to return the favor if I can.

Posted 20 March 2019 - 08:01 PM

I had time and read it all! Surprises and surprises!

I guess that when a new member arrives, this should be the first asked question.

How many thousands don't know that. Do you think that goes for every antidepressants?

And in what food do we find magnesium? Thank you!

#5 fishinghat

fishinghat

    Site Partners

  • Active Members
  • PipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPipPip
  • 12,554 posts
  • LocationMissouri

Posted 21 March 2019 - 08:35 AM

I did a search of he medical journals and found no research on magnesium in relations to other antidepressants. Obviously a lot of work needs to be done on this subject.

Magnesium is found in many vegetables but especially abundant in beans.

#6 invalidusername

invalidusername

    Site Partners

  • Site Supporter
  • 5,335 posts
  • LocationKent, UK

Posted 21 March 2019 - 04:20 PM

Absolutely. There are so many of these "super" absorbant types out there which should absolutely not be taken with a majority of medication. At least not at the same time. I anticipate that because of metabolisms and so forth that such issues can be subjective to a degree as well. It is research that doesn't hold much in the way of recognition and funding I guess - so like everything else, it is a case of waiting for the unsuspecting public to suffer first!!





0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users