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New To The Weaning Process

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#1 k2mike3344



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Posted 23 July 2019 - 12:30 PM

Hi there,


I am currently taking 30mg of cymbalta for nerve pain and axiety due to this pain.  I have 2 herniated discs in my neck.  I have had a few treatments over the last year and I feel the need to wean off of the meds.  My doctor has me taking 30 then 20mg every other day.  Yesterday, we decided to start using prozac.  he said when i start taking 20mg prozac, I should cease the cymbalta due to the low dosage.  I wanted to see if this was a good method.  I am having minor withdrawals from the current 30/20 method such as irritability and brain fog.  




#2 fishinghat


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Posted 23 July 2019 - 12:41 PM

Welcome Mike.


The every other day thing is not recommended by the FDA as Cymbalta has only a 12 hour half-life. SO you are raising your blood levels and then dropping your blood levels over and over. This causes a repeat of the withdrawal.


As far as switching to Prozac this approach is fairly normal. It takes Prozac up to 8 weeks to fully kick in so you might experience some withdrawal effects while you wait for it to kick in.

#3 k2mike3344



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Posted 23 July 2019 - 03:59 PM

Thank you!  To further clarify, I am taking 30mg on Monday, the 20mg on Tuesday, then 30mg Wed...etc right now for cymbalta, so I am not skipping a day, just alternating meds.  My last day of cymbalta is wed night, followed by Prozac 20mg on thursday morning.  


I am hoping this will work:)




#4 invalidusername


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Posted 23 July 2019 - 04:27 PM

Hi Mike - and a welcome from me...


Hat understood what you meant as noted in your above reply, and as he rightly said, this is not a recommended withdrawal. 30mg of Cymbalta is not a great deal, but the withdrawals effect people in different ways. 20mg of Prozac is more or less the equivalent, but I wouldn't have advised a direct switch. Your doctor is doing this to follow protocol of how to switch between AD's of 2 different classes (SSRI and SNRI), whereby you stop one - ideally a washout period - then start the new, but at low doses, it is far better to cross knowing that risks are very minimal. 


I would at least consider a little longer to go to 20mg Cym, then 15mg and start on 10mg Prozac, and then just 20mg Prozac. This will ease a lot of the potential symptoms incurred by a direct switch. 


That said, as it is a low dose, you may be fine. Either way, we are here to support you. If we can be of any help, just shout.



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