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Brands of capsules that members mentioned they used
FH ‐ These are the specific empty capsule brands that members have mentioned in
Other capsule info.
Cymbalta capsules are not enteric coated, only the individual beads are. Eli Lilley
uses gel capsules. The basic gel capsules work fine and can not only be bought on
line but also through your local compounding pharmacy.
Section 11 of the data sheet that comes with Cymbalta says it is a gelatin capsule
with enteric coated beads and the beads are designed to prevent contact with
"Duloxetine is rapidly hydrolyzed in acidic media to naphthol, which has no
antidepressant activity. To overcome this issue, the pellets inside the duloxetine
capsule are enteric coated, but the capsule is not. This enteric coating of the pellets
resists dissolution until pellets reach a segment of the gastrointestinal tract where
the pH is favorable. "
(Breckenridge)'s insert, which reads:
"Each capsule contains enteric‐coated pellets of 22.4, 33.7, 44.9 or 67.3 mg of
duloxetine hydrochloride equivalent to 20, 30, 40 or 60 mg of duloxetine,
respectively. These enteric‐coated pellets are designed to prevent degradation of
the drug in the acidic environment of the stomach. Inactive ingredients include
Summary of Cymbalta Withdrawal Information ‐ www.cymbaltawithdrawal.com
ammonium hydroxide, black iron oxide, hypromellose, methacrylic acid copolymer
dispersion (methacrylic acid‐ethyl acrylate copolymer, polysorbate 80, sodium lauryl
sulfate), potassium hydroxide, propylene glycol, shellac, sucrose, sugar spheres
(maize starch, sucrose), talc, titanium dioxide, triethylcitrate, and hard gelatin
capsules (gelatin, titanium dioxide). The 20 mg hard gelatin capsule colorant is
yellow iron oxide."
Enteric coated capsules ‐ more information
Eli Lilley Patent information
The patent information for Cymbalta manufacturing.
All "Duloxetine" data sheets say the capsules are hard gelatin except Activas, Teva,
Cipla, Heritage, Inventia, Lupin, Solco, Sun Phartmaceutical, Zydes and Ascend which
did not state the construction of the capsule. In addition, Camber brand is not
enteric coated PELLETS but are only film coated only. Film coated is made of the
same material but thinner and does not meet the FDA required digestion time to be